AB0478 RATES OF REMISSION IN PATIENTS WITH PSORIATIC ARTHRITIS TREATED IN TERTIARY CARE (2024)

FAQs

AB0478 RATES OF REMISSION IN PATIENTS WITH PSORIATIC ARTHRITIS TREATED IN TERTIARY CARE? ›

Remission was achieved at least once by 118 pts (59.9 %) and varied between 16.2% (DAPSA-REM) and 38.1% (DAS28-REM) at clinical visit. State of remission occurred at a median of 1 year (IQE 0-3.8) after the index visit. 57 (48.3%) pts achieved the first remission state within the first year of treatment.

Remission rates were 33%/40%/45%/56% for men and 17%/23%/24%/32% for women. For patients <45 years at diagnosis, 6-months LUNDEX-adjusted remission rate for pain was 28% vs. 18% for patients ≥45 years. Conclusion In 12,262 biologic-naïve PsA patients, 6 months treatment with TNFi reduced pain by approximately 50%.

PsA is a chronic condition, which means there's no cure. Medications can treat its symptoms, however, and PsA isn't life-threatening. Some research suggests that people with PsA have a slightly shorter life expectancy than the general population.

Results: Among 1490 patients followed over 15062.8 patient-years, 225 (15%) confirmed deaths were recorded (111 females, 114 males). The overall SMR was 0.92 (95% CI: 0.81-1.05), the sex-specific SMRs were 1.08 (95% CI: 0.89-1.30) for females and 0.81 (95% CI: 0.66-0.97) for males.

Nonsteroidal anti-inflammatory drugs (NSAIDs)

For both psoriasis and PsA, NSAIDs are a common first-line treatment. Typically available over the counter, NSAIDs include aspirin, ibuprofen (Advil), and naproxen sodium (Aleve). Your doctor may provide a prescription-strength NSAID if appropriate.

Studies show that some patients had a recurrence within six months of stopping medication and most of them flared within the first two to three months. It appears that though the disease may quiet down during remission, it doesn't cease to exist.

The Odds of Remission

Because the definition of RA remission has been subjective in the past, published rates vary greatly, ranging from as little as 10% to more than 60%. The most important factor is early diagnosis and aggressive treatment.

Both psoriatic arthritis and psoriasis are chronic diseases that worsen over time. However, you might have periods when your symptoms improve or go away temporarily.

Like psoriasis, psoriatic arthritis is a chronic condition. It can worsen over time, but you may also have periods of remission where you don't have any symptoms. It doesn't have a cure, but treatment can make a difference.

Qualifying for disability benefits

You can apply when PsA makes it difficult or impossible to perform a job. While you do not need to have a disability for a certain amount of time before you apply, you'll need to show that PsA will prevent you from working for at least 12 months.

How close are we to curing psoriatic arthritis? ›

There is no cure for psoriatic arthritis (PsA) yet, but research into effective therapies is ongoing. Treatment options currently include medications to reduce inflammation, pain, and skin symptoms.

It is possible to get psoriatic arthritis covered under critical illness insurance. However, before a provider can make a decision regarding your lump-sum payment, they will take into consideration factors such as the date of your diagnosis, how severe your symptoms are and what type of treatment you're receiving.

There have been at least 34,000 reports to the U.S. Food and Drug Administration of people who died while using biologic drugs since 2004, according to an extensive analysis by the Milwaukee Journal Sentinel of data from the agency.

These drugs can slow the progression of psoriatic arthritis and save joints and other tissues from permanent damage. The most commonly used disease-modifying antirheumatic drug (DMARD) is methotrexate (Trexall, Otrexup, others). Others include leflunomide (Arava) and sulfasalazine (Azulfidine).

Some people find that joint pain and swelling gets better in the summer. It's not always clear why, but many people with psoriatic arthritis find that their symptoms improve when the weather gets warm. For those who also struggle with skin symptoms (psoriasis), their plaques may also improve during the summer months.

Psoriatic arthritis (PsA) is a common and difficult-to-treat condition that often occurs with psoriasis. The drug company UCB recently developed a new PsA treatment called Bimzelx. Bimzelx appears to be effective even in individuals who have not previously responded to treatment.

No cure exists for psoriatic arthritis. Treatment focuses on controlling inflammation in your affected joints to prevent joint pain and disability and controlling skin involvement.

Psoriatic arthritis disease progression is not inevitable. When your PsA is treated with medications that reduce immune system overactivity, you can reduce your disease activity to a point that it's no longer causing significant symptoms or increasing the risk of long-term health issues.